Ozzy & Drix
Ozzy must keep Nick O'Teen from getting to the brain where he will cause Hector to smoke.
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Phil LaMarr
Osmosis Jones (voice)
Jeff Bennett
Drix (voice)
Alanna Ubach
Mayor Paul Spryman / Hector's Mom (voice)
Justin Cowden
Hector Cruz (voice)
Tasia Valenza
Maria Amino (voice)
Jim Cummings
Police Chief Gluteus (voice)
Frank Welker
Tar (voice)
Tara Strong
Ashley / Carbon Monoxide (voice)
Tim Curry
Nick O'Teen (voice)
Rino Romano
Jude (voice)
Rob Paulsen
Travis Lum (voice)
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