Ozzy & Drix
Drix tries to learn how to act ""street"" and ends up helping an acne germ create a huge zit on Hector's face.
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Phil LaMarr
Osmosis Jones (voice)
Jeff Bennett
Drix (voice)
Alanna Ubach
Mayor Paul Spryman / Hector's Mom (voice)
Justin Cowden
Hector Cruz (voice)
Tasia Valenza
Maria Amino (voice)
Jim Cummings
Police Chief Gluteus (voice)
Danny Bonaduce
Smirch (voice)
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