Pants in Space

Tom Kenny

Jacob P. 'Jake' Spidermonkey / Henry Armadillo (voice)

Grey DeLisle

Ingrid Giraffe / Guadalupe 'Lupe' Toucan / Mrs. Geraldine Sharon Warthog (voice)

Rick Gomez

Windsor Gorilla / Slips Python (voice)

Phil LaMarr

Virgil 'Bull' Sharkowski (voice)

Nika Futterman

Adam Lyon / Miss Chameleon (voice)

Cree Summer

Kerry (voice)

Brian Doyle-Murray

Coach Tiffany Gills (voice)

Maurice LaMarche

Principal Poncherello Pegone Pixiefrog (voice)