Season 1

Doctors are baffled by a woman's mysterious respiratory problem. Featuring Cushing's syndrome, gout, carcinoid cancer.

A child with celiac disease is intolerant of gluten; a woman has her left frontal lobe removed to stop seizures; another woman suffers from fatigue and mood swings. Featuring celiac disease, mitral valve prolapse (MVP), epilepsy.

A child with Hurler's disease undergoes a stem-cell transplant procedure; a woman is diagnosed with myasthenia gravis; A father has seizures and fainting spells due to a heart arrhythmia. Featuring Hurler syndrome, myasthenia gravis, cardiac arrhythmia.

A young boy's body is not producing antibodies to fight infections; a cancerous tumor must be removed; a woman loses the ability to walk. Featuring common variable immunodeficiency (CVID), gastrointestinal stromal tumor (GIST), reflex sympathetic dystrophy (RSD).

A baby who cries and holds her cheek; a woman who gained 100 pounds in three months and developed severe acne; and an avid athlete struggling to catch his breath. Featuring trigeminal neuralgia, polycystic ovary syndrome and alpha-1 antitrypsin deficiency.

A 12-year-old girl experiences abdominal pains and severe headaches until she is diagnosed with a retroflexed odontoid and Chiari One malformation; a firefighter and paramedic is diagnosed with acquired immunodeficiency syndrome (AIDS).

A 5-year-old has a persistent fever and stomachache. A man crippled with a neck tilt. A woman falls ill after traveling abroad. Featuring Crohn's disease, cervical dystonia, brucellosis.

Two brothers suffer the same heart problem. Joanne suffers from joint pain, mouth ulcers, genital sores, skin lesions, and vision problems. Featuring Barth Syndrome, Behcet's Disease