The Substance
"Have you ever dreamt of a better version of yourself?"
Where to Watch
HBO Max Amazon Channel 
MUBI 
MUBI Amazon Channel 
HBO Max Overview
A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.
Horror Science Fiction
Top Cast
Demi Moore
Elisabeth
Margaret Qualley
Sue
Dennis Quaid
Harvey
Edward Hamilton-Clark
Fred
Gore Abrams
Oliver
Oscar Lesage
Troy
Christian Erickson
Man at Diner
Robin Greer
Male Nurse
Tom Morton
Doctor
Hugo Diego Garcia
Diego - Boyfriend
Daniel Knight
Casting Director
Jonathon Carley
Assistant Casting Director
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Release Schedule
Theatrical Sep 7, 2024
Digital Oct 31, 2024
Physical Jan 21, 2025
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